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Discover the latest in African health data infrastructure, biobanking innovation, and our impact across the continent.

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Publications

Mediator Kinase Inhibitor Selectivity and Activity in Colorectal Cancer

Building Equity Into Rare Disease Research Through Biobanking: Lessons From PIK3CA-Related Overgrowth Spectrum Disorders

Assessing the mechanism and therapeutic potential of modulators of the human mediator complex-associated protein kinases

Discovery of Potent, Selective, and Orally Bioavailable Small- Molecule Modulators of the Mediator Complex-Associated Kinases CDK8 and CDK19

A selective chemical probe for exploring the role of CDK8 and CDK19 in human disease

De Novo Missense Substitutions in the Gene Encoding CDK8, a Regulator of the Mediator Complex, Cause a Syndromic Developmental Disorder

67 Kenyan patients. Different diagnoses. One recurring genetic pattern that only became visible once the data was properly connected. This […]